Modulation by colonic fermentation of LES function in humans.

Les variations dans la fermentation des glucides par Salmonella gallinarum et Salmonella pullorum. Leur intérêt diagnostic

Colonic fermentation: a neglected topic in human physiology education.

Human physiology textbooks tend to limit their discussion of colonic functions to those of absorbing water and electrolytes and storing waste material. However, the colon is a highly active metabolic organ, containing an exceedingly complex society of microbes (1). By means of fermentation, gastrointestinal microbes break down nutrients that cannot be hydrolyzed by mammalian host enzymes and th...

Non-digestible food ingredients, colonic microbiota and the impact on gut health and immunity: a role for metabolomics.

Increasing health issues related to immune and gut function such as inflammatory disorders, resistance to infections and metabolic syndrome demand modern analytical approaches to accelerate nutritional research aimed at health promotion and disease prevention. Gut microbial-human mutualism endows the host 'superorganism' with a fitness advantage including nutritional, immune and intestinal heal...

Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides.

Resistant starch (RS) is starch and products of its small intestinal digestion that enter the large bowel. It occurs for various reasons including chemical structure, cooking of food, chemical modification, and food mastication. Human colonic bacteria ferment RS and nonstarch polysaccharides (NSP; major components of dietary fiber) to short-chain fatty acids (SCFA), mainly acetate, propionate, ...

Biological functions of SLC5A8, a candidate tumour suppressor.

SLC5A8 is a candidate tumour suppressor gene that is silenced in colon cancer, gastric cancer and possibly other cancers in humans. This gene codes for a transporter belonging to the Na(+)/glucose co-transporter gene family (SLC5). The cancer-associated silencing of the gene involves hypermethylation of CpG islands present in exon 1 of the gene. SLC5A8 is expressed in colon, ileum, kidney and t...